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Circumcision and HIV Case Study – Fall 2026

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Circumcision and HIV Case Study – Fall 2026.pdf (4.68 MB) Question 2 In the Orange Farm study, what is the relative risk among those randomized to the noncircumcision comparison group compared to those in the circumcision study group? How do you interpret this relative risk? The relative risk also allows us to calculate the percent efficacy or the attributable risk percentage. That is the percentage of HIV infection that can potentially be prevented among men without circumcision by performing male circumcision. When the relative risk is more than one (i.e., the factor that increases the risk is in the numerator of the relative risk equation), the formula for percent efficacy is:

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