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[Answered]: A 32-year-old woman with bipolar disorder has…

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A 32-year-old woman with bipolar disorder has been maintained on 900 mg/day of lithium. She was doing well for a long time and had even been able to lose the weight she had initially gained with lithium. She broke up with her boyfriend 5 months ago and has been feeling depressed ever since. You augment her with 300 mg/day of quetiapine, but after several weeks she complains of weight gain and wants to change medications. Blockade of which two receptors was most likely responsible for this weight gain induced by quetiapine?

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