Which patient characteristic contraindicates the use of zonisamide

Which patient characteristic contraindicates the use of zonisamide? geoquad Need for rapid intravenous seizure control in an acute setting geoquad Concurrent use of medications metabolized by cytochrome P-450 enzymes geoquad Presence of mild gastrointestinal discomfort at baseline geoquad History of severe allergic reaction to sulfonamide antibiotics